BIOL 133 Week 12 Quiz | Assignment Help | APUS
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BIOL 133 Week 12 Quiz | Assignment Help | APUS
Week 12 Quiz
Question 1 of 10
Epigenetics refers to a special kind of hereditary
mechanism. Epigenetic changes do not change the DNA nucleotide sequence, yet
their effect on gene expression can last for several generations.
In one surprising study, it was found that the
grandsons of men who suffered a famine were less likely to die of
cardiovascular disease. The experience of famine made some cardio-protective
change in the sperm of those grandfathers that was passed on.
What type of change was likely responsible?
o
phosphatase levels
o
transcription factor activity
o
histone acetylation or DNA methylation
o
ubiquitin tagging
_________ is the first protein to bind to mRNA to
being initiation of translation.
o
TFIIA
o
eIF-2
o
TFIID
o
60S ribosomal subunit
o
40S ribosomal subunit
Question 3 of 10
What would happen if there were a mutation in the
operator of the trp operon?
o
the trp operon woudl not be able to
express the genes
o
the CAP protein couldn't bind, therefore
shutting off the genes
o
the trp operon would continuously express
the genes
o
RNA polymerase could not recognize the
promoter, so transcription would not occur
Question 4 of 10
What part of the ribosome is important in catalyzing
peptide bonds?
o
the E site
o
the methyl guanosine cap
o
the rRNA
o
the ribosomal proteins
Question 5 of 10
The portions of the mature mRNA where RNA-binding
proteins can attach in order to change RNA stability are known as
o
enhancers
o
untranslated regions
o
codons
o
poly-A-tails
o
operators
Question 6 of 10
A gene is made up of three exons (numbered
consecutively) with two introns (intron 1 between exons 1 and 2 and intron 2
between exons 2 and 3). What would happen if there were a mutation at the 3’
splice site of intron 1?
o
mRNA with exons 2 and 3 along with intron
2
o
mRNA with all three exons and both introns
o
mRNA with only exons 2 and 3
o
mRNA with all three exons along with intron
1
Question 7 of 10
Enhancers located hundreds of bases upstream of a gene
can be brought to the promoter by _________.
o
initiation factors
o
trascription factors
o
DNA bending proteins
o
distal control elements
Question 8 of 10
In eukaryotes, where would a protective modification
be found on mRNA?
o
on the 5' end
o
on the 3' end
o
on both the 5' end and the 3' end
o
on neither the 5' end nor the 3' end
Question 9 of 10
Overexpression of miRNAs can lead to a decrease of
protein expression associated with some forms of cancer. What could a drug do
to counter this effect?
o
increase promoter activity of the miRNA
genes
o
decrease expression of RNA polymerase
o
increase expression of RISC
o
decrease expression of miRNA
Question 10 of 10
If every cell in the body gets the same DNA, how do
the cells of an embryo make different structures and take on different roles?
(Select all that apply.)
o
Different transcription factors are active
in different cells.
o
Different transcription factors are
encoded in the DNA.
o
Genes are spliced differently in different
cells.
o
Translation is regulated so that different
cells may make more of certain proteins.
o
Some cells lack ribosomes while others use
them.
o
Cells delete a set of unused genes from
their chromosomes.
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