Plan personal work goals project
1. Answer ALL parts a) – d).
Compound 1 is an anti-arrythmia drug that is obtained as a single enantiomer using the following one-pot, multi-enzyme mixture:
a) Draw structures for compounds A and B. [4]
b) Which compound(s) is (are) consumed in this de-racemisation process? [4] c) Briefly explain why the enzyme formate dehydrogenase is added to the reaction mixture. [6]
d) Write a curly arrow mechanism for the following reaction in the cascade that clearly
shows the role of the co-factor NADH.
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