Effectiveness of chlorhexidine bath in preventing central line infection

 In patients with central lines, what is the effectiveness of daily chlorhexidine bath compared to weekly or as needed dressing changes to reduce infection within the first three months of insertion?

Referenes has to be:

Furuya, Y., Dick, A., Perencevich, E., Pogorzelska, M., Goldman, D., & Stone, P. (2011). 	Central line bundle implementation in US intensive care units and impact on 	bloodstream infections. PLoS ONE, 6(1), 1-6.  

Graling, P., & Vasaly, F. (2013). The effectiveness of 2% CHG Cloth Bathing for Reducing 	Surgical Site Infections. AORN Journal, 97(5): 547-551.

Kim, J., Holtom, P., & Vigen, C. (2011). Reduction of catheter-related bloodstream infections 	through the use of a central venous line bundle: Epidemiologic and economic 	consequences. American Journal of Infection Control, 39(8), 640-646. 

Klinworth, G., Stafford, J., O’Connor, M., Leong, T., Hamley, L., Watson, K., Kennon, J., Bass, 	P., Cheng, A. C., & Worth, L. (2014). Implementation of a successful hospital-wide 	initiative to reduce central line–associated bloodstream infections. American Journal of 	Infection Control, 42(6), 685-687.

McAlearney, A., Hefner, J., Robbins, J., Harrison, M., & Garman, A. (2013). Preventing central 	line-associated bloodstream infections: A Qualitative Study of Management Practices. 	Infection Control & Hospital Epidemiology, 36(5), 557-563. 

Power, J., Peed, J., Burns, L., & Davis, M. (2012). Chlorhexidine bathing and microbial 	contamination in patients’ basin. American Journal of Critical Care, 21(5), 338-342.

Quach, C., Milstone, A, Perpe, C., Bonenfant, M., Moore, D., & Perreault, T. (2014). 	Chlorhexidine Bathing in a tertiary care neonatal intensive care unit: Impact on central 	line–associated bloodstream infections. Infection Control & Hospital Epidemiology, 	35(2), 158-163.

 Richardson, J., & Tjoelker, R. (2012). Beyond the central line-associated bloodstream infection 	bundle: the value of the clinical nurse specialist in continuing evidence-based practice 	changes. The Journal of Advanced Nursing Practice, 26(4), 205-211. 

 Scheithauer, S., Lewalter, K., Schroder, J., Koch, A., Hafner, H., Krizanovic, V., Nowicki, K., 	Hilgers, R.-D., & Lemmen, S. (2014). Reduction of central venous line-associated 	bloodstream infection rates by using a chlorhexidine-containing dressing. Infection, 	42(1), 155-159.
 
U.S. Department of Health and Human Services. (2011). Health-care-associated infection (HAI). 	Retrieved 10/21/2016 from http://www.hhs.gov/ash/initiatives/hai/index.html

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