NUR 318 Week 3 Assignment Help | La Salle University

NUR 318 Week 3  Assignment Help | La Salle University

Module 3 Assignment: Vericite Submission for Cardiac Disease/Hypertension

Please post answer to your assigned question to vericite prior to submitting it to the discussion.

The percentage match must not be much  greater than 10%. 

The following content is partner provided

What is the rationale for the use of Sacubitril & valsartan in heart failure?
Over the last few years, heart failure has become a major public health issue in the United States, with more than 1 million people hospitalized yearly.
(Ho Je, Lyass A, Lee DS, et al, 2013).Many medications have been used to treat heart failure.Sacubitril/Valsartan is a first in class medication that has proven to reduce the mortality rate in patients having chronic heart failure.The rationale of this medication is that, according research, it does two things.


It breaks down B-type Natriuretic Peptide 
(BNP), which has a beneficial effect in the treatment of heart failure.

It inhibits the formation of angiotensin II. Angiotensin II causes angioedema, which is bad for patients with heart failure.So by inhibiting angiotensin II, it eliminates the adverse effect of fluid buildup.

 

There's a lot of technicalities to the pathophysiology of Sacubitril/Valsartan, but the above mentioned point are a gist of the benefits of the combination medications.


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